Method for diagnosing the presence of gluten intolerance

Method of extracorporeal diagnosis of the food sensitivity or intolerance to gluten in patients.

Title of the patent Method and kit for the diagnosis and monitoring of sensitivity and intolerance to foods
Thematic area Chemistry and biotechnology
Ownership Alma Mater Studiorum - Università di Bologna
Inventors Enzo Spisni, Massimo Campieri
Protection Italy
Licensing status Available for licensing agreement
Keywords Food Intolerances, gluten sensitivity, screening test, gluten, blood sample
Filed on Sep 04, 2012

Most gastroenterologists agree on the possibility that there may be personal sensitivities to certain foods, probably linked to phenomena of innate immunity. These sensitivities are different from allergies and adverse reactions to foods, which can be demonstrated by tests accepted by conventional science (immunological, biochemical and histological). To date, their existence cannot be demonstrated with certainty, nor is it possible to diagnose it with conventional methods. The sensitivity to gluten, for a long time considered to be a psychosomatic reaction, has become a disease ascertainable only recently, following studies who have demonstrated its existence.

The method identifies some markers of sensitivity or intolerance to the protein component of the food (typically gluten sensitivity or celiac disease), and sets up a test in the form of a kit for the diagnosis and therapy of these states.

The method permits with biochemical parameters to evaluate the intensity of responses to gluten (and consequently the gravity) and the effects of a gluten-free diet or after gluten reintroduction of diet.