Endodontic bioactive cement

Innovative endodontic cement, composed of calcium silicate mineral powder and light-curing resin, characterized by high biocompatibility and bioactivity.

Title of the patent Endodontic bioactive cement
Thematic area Chemistry and biotechnology
Ownership Alma Mater Studiorum - Università di Bologna
Inventors Carlo Prati, Maria Giovanna Gandolfi
Protection Italy
Licensing status Available for licensing agreement
Keywords Endodontic cement, calcium-silicate mineral cement, light-curing cement, root-end filling, bioactive cement, apatite, fast setting time, Portland cement
Filed on Dec 29, 2009

In the dental sector materials able to ensure the repair and functional rehabilitation of teeth damaged by degenerative process are strongly required. In particular the need is for materials supporting the formation of new bone and interact with the tissue present outside of the filling.
The market offers biomaterials for endodontic use which are applicable both to external and internal bone tissue, contiguous to the dental tissue. There are also evidence suggesting that the study of bone tissue regeneration in dentistry could be a good experimental model for the study of other types of bone diseases. In particular, attention is focused on the development and testing of new bioactive materials, having osteoconductive and osteoinductive activities.

An innovative endodontic cement, composed of calcium-silicate mineral powder and a light-curing resin has been developed to obtain a new material for clinical use in endodontic practice characterized by fast setting, bioactivity, biocompatibility and suitable handling characteristics.

Main advantages:

- easy to use;

- rapid hardening;

- light curing;

- reduced run-off from the surgical site;

- low solubility;

- bioactivity, i.e. capacity to produce apatite in the presence of body fluids;

- osteoconductive properties;

- hydrophilic;

- good sealer;

- low porosity / permeability.