84924 - Pharmaceutical Technology and Galenical Preparations Laboratory

Academic Year 2022/2023

  • Docente: Paolo Blasi
  • Credits: 11
  • SSD: CHIM/09
  • Language: Italian
  • Moduli: Paolo Blasi (Modulo 1) Teresa Cerchiara (Modulo 2) Paolo Blasi (Modulo 3) Teresa Cerchiara (Modulo 4)
  • Teaching Mode: Traditional lectures (Modulo 1) Traditional lectures (Modulo 2) Traditional lectures (Modulo 3) Traditional lectures (Modulo 4)
  • Campus: Bologna
  • Corso: Single cycle degree programme (LMCU) in Pharmacy (cod. 9219)

Learning outcomes

The aim of this course is to give a broad understanding of the basic principles and technologies applied in the preparation of different pharmaceutical dosage forms: powders, granules, tablets, capsules, solutions, eye drops, ointments, creams, emulsions, suspensions, gels, suppositories.

Course contents

Pharmaceutical technology (Module 1 – Prof. Paolo Blasi)

Introduction to medicinal products and dosage forms. Principles of biopharmaceutics.

Solid dosage forms. Powders. Granules and granulation. Tablets and compaction. Coating of tablets and multiparticulates. Hard and soft capsules. Suppositories and pessaries.

Liquid dosage forms. Interfacial phenomena. Properties of solutions, suspensions, emulsions. Syrups. Sterilization and sterile dosage forms. Parenterals.

Pharmaceutical technology (Module 2 – Prof. Teresa Cerchiara)

Semisolid dosage forms. Principles of rheology. Creams, ointments, gels and pastes. Vegetable drugs preparations.

Galenic Laboratory (Modules 3 and 4 – Prof. Paolo Blasi and Prof. Teresa Cerchiara)

Preparation of the following galenic formulations: capsules, syrups, suspensions, emulsions, creams, ointments, pastes, suppositories and pessaries. Calculation of price, packaging and labeling.

Readings/Bibliography

Pharmaceutical Technology

P. Colombo et al., Principi di tecnologia farmaceutica, CEA, 2015.

M.E. Aulton et al., Tecnologie farmaceutiche: progettazione e allestimento dei medicinali. EDRA, 2015.

Galenic Laboratories

F. Baratta et al., Manuale di galenica a uso umano e veterinario, CEA–Zanichelli, 2019.

F. Bettiol, Manuale delle preparazioni galeniche, Tecniche Nuove, 2016.

E. Ragazzi, Galenica pratica - Formulazione e tecnologia, Libreria Internazionale Cortina, 2006.

Italian and European Pharmacopoeias.

Slides presented during the course can not be considered as a substitute of the reference texts suggested above.

Teaching methods

Lectures (module 1, 40 hours; module 2, 16 hours) and practical experience in the Galenic laboratory (modules 3/4, 60 hours each one).

As concerns the teaching methods of this course unit, all students must attend Module 1, 2 [https://www.unibo.it/en/services-and-opportunities/health-and-assistance/health-and-safety/online-course-on-health-and-safety-in-study-and-internship-areas] online, while Module 3 on health and safety is to be attended in class. Information about Module 3 attendance schedule is available on the website of your degree programme.

Assessment methods

Modules 1 and 2 Oral exams.

Module 3 or 4 Preparation of a galenic formulation, calculation of price, packaging and labelling.

Teaching tools

Power Point presentations for the Modules 1 and 2 and laboratory notes for the Module 3 or 4  (available in https://iol.unibo.it).

Office hours

See the website of Paolo Blasi

See the website of Teresa Cerchiara

See the website of Teresa Cerchiara