08956 - Clinical Biochemistry

Academic Year 2021/2022

  • Docente: Stefania Evangelisti
  • Credits: 1
  • SSD: BIO/12
  • Language: Italian
  • Teaching Mode: Traditional lectures
  • Campus: Ravenna
  • Corso: First cycle degree programme (L) in Nursing (cod. 8474)

Learning outcomes

The student, at the end of the module, thanks to the knowledge of the fundamental principles of chemistry and organic molecules of biological interest, is able to evaluate the biological and biochemical parameters in biological and in vivo samples, also in relation to pathophysiological states, at different levels of structural organization, from single molecules to cells, tissues, organs, up to the whole organism.

Course contents

  • Introduction to the course.
  • Clinical biochemistry in vivo and ex vivo in the field of laboratory medicine.
  • The role of laboratory medicine in the clinical context.
  • Elements of organization of a biomedical laboratory.
  • Reference values and decision-making levels.
  • Performance of a diagnostic test: sensitivity, specificity, predictive value.
  • The pre-analytical, analytical and post-analytical phases of laboratory investigations.
  • Biological, pre-analytical and analytical variability.
  • Clinical indications, contraindications, side effects and complications.
  • Types of laboratory tests: routine, urgency, emergency.
  • Screening test.
  • From patient to laboratory test: patient preparation, sample collection, handling and storage
  • Examples of the role of the nurse in the classification of muscle disorders, in laboratory diagnostics of cerebrospinal fluid, in in vivo molecular diagnostics.

Readings/Bibliography

  • Teaching material in pdf
  • M. Ciaccio e G. Lippi, Biochimica Clinica e Medicina di Laboratorio, EDISES

Teaching methods

Frontal lessons with Power Point presentations

Assessment methods

Written test.

The evaluation of the knowledge acquired by the student is based on the administration of a single questionnaire consisting of 31 questions for the Integrated Course of Pathological Sciences, with multiple choice (4 possible choices) and a single correct answer. The questions are distributed proportionally to the CFUs of the individual disciplines that make up the integrated course. The total time allowed for the exam is 15 minutes. Students with certified SLD will be granted 5 additional minutes.

The grade is proportional to the number of correct answers (18 answers = 18 \ 30, 25 answers = 25 \ 30, 31 answers = 30 honors).

The exam is considered positively passed starting from 18 correct answers, corresponding to the mark of 18/30.

Teaching tools

Didactic material in Power Point presentations

Office hours

See the website of Stefania Evangelisti