- Docente: Giovanni Perini
- Credits: 6
- SSD: BIO/18
- Language: Italian
- Moduli: Giovanni Perini (Modulo 1) Giorgio Milazzo (Modulo 2)
- Teaching Mode: Traditional lectures (Modulo 1) Traditional lectures (Modulo 2)
- Campus: Bologna
- Corso: Second cycle degree programme (LM) in Molecular and cellular biology (cod. 8021)
Learning outcomes
Students will acquire notions about the basic molecular mechanisms responsible for epigenetic phenomena with a special emphasis on X-chromosome inactivation, allelic exclusion and DNA methylation dynamics during embryogenesis
Course contents
Lectures will deal with the following subject matters: X-chromosome inactivation, Genomic imprinting, Allelic exclusion, paramutation in plants, RNA interference, chromatin organization, DNA methylation dynamics during embryogenesis, HSP90 buffering.
Readings/Bibliography
Scientific papers from top ranked journals such as Cell, Science, and Nature.
Teaching methods
Standard lectures and paper-reading
Assessment methods
Written exam consisting in eight open questions and one problem, followed by an oral exam.
Teaching tools
Slides and papers from scientific journals
Office hours
See the website of Giovanni Perini
See the website of Giorgio Milazzo