00768 - General Pathology

Learning outcomes

At the end of the course the student knows the concept of disease, etiology and pathogenesis, the reversible and irreversible cell damage. The student knows the molecular and cellular bases of the acute and chronic inflammatory responses, of the reparative process and of the normal and pathological immune response; the student knows the etiopathogenesis of diseases of interest to the professional Orthopaedic Technician.

Course contents

Programme / Content

- Definition and aims of General Pathology. Concept of disease. Etiology and pathogenesis

- Cell adaptations: atrophy, hypertrophy, hyperplasia, metaplasia

- Reversible and irreversible cell damage

- Necrosis and apoptosis

- Normal immune response: cells and molecules of the immune system, humoral and cellular defense against infectious diseases

- General Pathology of microbial infections, focusing on post-surgical orthopedic infection.

- Acute inflammation. Etiology and signs, pathogenesis, cells and chemical mediators, vascular phenomena and formation of the exudate, cellular phenomena, chemotaxis and phagocytosis, fever and other systemic effects

- Chronic Inflammation

- Reparative process

- An outline of:

• Atherosclerosis and Arteriosclerosis

• Thrombosis and Haemostasis

• Diabetic Foot

• Anemia and Thalassemia

Readings/Bibliography

- Parola. Patologia Generale. Edises

- Pontieri, Elementi di Patologia Generale per i Corsi di Laurea in Professioni Sanitarie, 3a edizione, Piccin

- Poli-Columbano, Compendio di Patologia Generale e Fisiopatologia, Edizioni Minerva Medica

Teaching methods

Lectures and laboratory demonstrations

Assessment methods

Written examination on open questions

Teaching tools

Projecting slides and photomicrographs. The teaching materials will be provided directly by the Teacher.

Office hours

See the website of Carla Renata Arciola