- Docente: Carla De Giovanni
- Credits: 3
- SSD: MED/04
- Language: Italian
- Teaching Mode: Traditional lectures
- Campus: Bologna
- Corso: First cycle degree programme (L) in Biomedical Laboratory techniques (cod. 8484)
Learning outcomes
At the end of the course the student has expertise relating to:
fundamental principles of the etiology and pathogenesis, cellular
and tissue changes leading to reversible and irreversible damage,
the molecular and cellular bases of acute, chronic and repair
inflammatory response, the specific mechanisms of the adaptive
immunity, its defensive aspects and possible pathological
consequences; the etiopathogenesis of neoplastic transformation,
progression to malignancy and metastasis.
Course contents
INTRODUCTION AND FUNDAMENTAL CELLULAR PATHOLOGY
- Objectives, purpose and organization of the course.
- Etiology and pathogenesis, classification of etiologic factors.
- Cell injury : subletal alterations, apoptosis and necrosis.
- Cell ageing
- Cell adaptation : atrophy, hypertrophy, hyperplasia,
metaplasia, dysplasia.
DEFENSE MECHANISMS
- Innate immunity
- Adaptive immunity
- Acute and chronic inflammation
- Systemic responses and fever.
- Repair, regeneration and healing
- Immunopathology
- Transplants
- Vaccines
TUMOR BIOLOGY
- Benign and malignant tumors, nomenclature.
- Cancer epidemiology.
- Cancer genes: oncogenes and tumor suppressor genes.
- Inherited tumors.
- Cancer progression and malignant phenotype.
- Metastatic process.
- Immune response and cancer antigens.
- Chemical, physisical and infectious carcinogenic agents.
Readings/Bibliography
PONTIERI, Elementi di Patologia Generale, per i corsi di laurea in professioni sanitarie, 3a edizione, PICCIN 2011
Regueiro Gonzalez e coll.- Immunologia. Biologia e patologia del sistema immunitario., PICCIN 2011
Teaching methods
Lectures
Interactive summaries
Assessment methods
Written tests will be administered in itinere, consisting of both multiple choice and open questions.
Oral exam.
In itinere tests and/or oral exam will contribute to the final mark of the Integrated Course 39275 PATOLOGIA GENERALE, GENETICA MEDICA E ONCOLOGIA MEDICA, with proportion to the number o credits assigned to General Pathology
Teaching tools
Video projector, PC
Didactic material showed in lectures can be downloaded by students from e-learning website (login with student credentials). Students are invited to attend lectures bringing a printed copy of didactic materials.
Office hours
See the website of Carla De Giovanni