Unibo Team Leader: Dott. Uberto Pagotto, Dip. di Medicina Clinica
NeuroFAST is a multidisciplinary project, involving twelve teams from 7 countries, to explore the neurobiology of addiction and eating behaviour and the complex socio-psychological forces that lead to its dysregulation. These forces include dietary components (including highly palatable foods and alcohol), some of which may have addictive properties, but also cultural and social pressures, everyday stressors, and family-genetic influences on these. The project will provide new data from human studies, including human nutritional studies, that is needed to inform Health Policy initiatives.
This will be underpinned by state-of-the-art mechanistic research to establish a solic scientific basis for this advice. The European added value lies in building up the necessary critical mass in several fields of expertise: psychology, epidemiology, human genetics related to eating disorders, human nutrition, eating and addictive behaviour disorders, endocrinology, human brain imaging, together with studies of the basic mechanisms of eating behaviour and addiction, (neuro)endocrine regulators, stress, opiate dependence, and cannabinoid actions. To provide scientific support for European public health policies, a focus will be on a socio-psychological analysis of determinants of food addiction
and substance abuse, and of how risk factors like stress in the workplace are driving addictive behaviour. We will establish an evidence base for inter-relationships, linking eating disorder research with obesity research, stress research and addiction research, and involving studies of selected
individual food components using novel designed foods with controlled components. In summary, we will use a synergistic combination of controlled laboratory studies, characterization of patient groups, and examination of real world scenarios based on epidemiological community samples that will be relevant to policy development.
Coordinator
GOETEBORGS UNIVERSITET (Sweden)
Other participants
ALMA MATER STUDIORUM-UNIVERSITA DI BOLOGNA
- Dip. di Medicina Clinica
- Resp. Scientifico: Dott. Uberto Pagotto
UNIVERSITAIR MEDISCH CENTRUM UTRECHT (The Netherlands)
THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (UK)
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE (UK)
UNIVERSITAETSKLINIKUM ESSEN (Germany)
THE UNIVERSITY OF EDINBURGH (UK)
TECHNISCHE UNIVERSITAET DRESDEN (Germany)
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA (Spain)
INSTITUTE OF EXPERIMENTAL MEDICINE - HUNGARIAN ACADEMY OF SCIENCES (Hungary)
NIZO FOOD RESEARCH BV (The Netherlands)
CONSIGLIO NAZIONALE DELLE RICERCHE (Italy)
FONDAZIONE TOSCANA GABRIELE MONASTERIO PER LA RICERCA MEDICA E DI SANITA' PUBBLICA (Italy)
Start date 01/04/2010
End date 31/03/2015
Duration 60 months
Project cost 7.751.494,60 EURO
Project Funding 5.999.984 EURO
Subprogramme Area Stress, addiction and eating behaviour
Contract type Collaborative project-Large-scale integrating project